Bone and Tissue Consortium
Campus collaboration leads to clinical trials and commercialization
With funding from the U.S. Army, what started as the University of Missouri—Kansas City and Missouri University of Science and Technology’s Consortium on Bone and Tissue Repair and Regeneration has expanded to more than 35 faculty and graduate students, including faculty in the UMKC’s School of Dentistry, Bone Biology Research Program and the Center of Excellence in Mineralized Tissues, as well as Biomedical Engineering at Saint Louis University. Research is being conducted on bone biology, designing bioactive glass scaffolds for repairing broken and diseased bone, developing biodegradable sensors for in-vivo use, and utilizing a new family of bioactive borate glasses to heal chronic wounds in animals and humans.
This collaboration played a key role in the establishment of The Center for Bone and Tissue Repair and Regeneration at Missouri S&T, and has produced more than 85 published technical papers on bioactive materials/glass in the last five years and led to UM being granted five U.S. patents (four pending), several of which have been licensed to companies that are now commercializing this UM technology.
One commercial product for veterinary use, Rediheal™, is already being used to heal traumatic wounds in animals and a second product, Deramfuse™ is being developed for human use. Other important participants in this collaboration are the Phelps County Regional Medical Center (PCRMC) and MO-SCI Corp in Rolla, Mo. MO-SCI Corp, a manufacturer of glasses for the health care industry, has provided several bioactive glasses for research purposes, including the borate glass fiber that was used by the PCRMC in a recently completed pre-clinical trial to treat patients with chronic, non-healing wounds. The success of this “cotton candy-like” fiber in healing several types of wounds has received international attention.